Sentence examples for and efficacy in a from inspiring English sources

This research has resulted in the design and synthesis of a series of molecules, one of which was recently evaluated for safety and efficacy in a clinical trial.

A compound from this series demonstrated rat oral bioavailability and efficacy in a bovine articular cartilage explant model.

The corresponding cyclohexylalanine derivatives such as 25 afforded improved PK exposure and efficacy in a murine OGTT experiment.

Before the F.D.A. approves a new medicine, the drug must survive testing for safety and efficacy in a three-stage sequence of trials, each of them involving a larger sample and more rigorous methods.

The Division has a long and distinguished history of high-impact research in renal transplantation, and pioneered the use of complete steroid avoidance, demonstrating safety and efficacy in a multicenter clinical trial.

Adeno-associated virus (AAV) vectors have emerged as a gene-delivery platform with demonstrated safety and efficacy in a handful of clinical trials for monogenic disorders.

This compound showed excellent pharmacokinetics and efficacy in an ovariectomized (OVX) rhesus monkey model.

To test selectivity and efficacy in an in vivo target, calmidazolium, the best channel blocker of capsaicin-induced Ca2+-uptake in TRPV1-NIH3T3 cell was tried in sensory neurons, expressing TRPV1 endogenously.

In conclusion, this study described some pharmacodynamic characteristics of the novel adenosine A1R-specific antagonist SLV329 and demonstrated its long-term safety and efficacy in an animal model of liver cirrhosis.

The study aim is to evaluate its safety and efficacy in an animal model that combines liver failure with sepsis.

The purpose of this study was to develop a novel treatment for knee OA using MRgFUS, and to validate its safety and efficacy in an initial case series.