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Usability is a key factor in ensuring safe and efficacious use of medicines.
In order to ensure the safe and efficacious use of ULM, robust clinical governance processes need to be in place with adequate information available for patients.
Well-designed preclinical and translational studies to establish the safe and efficacious use of cell-therapies to enhance bone regeneration are needed.
These observations create an interesting link between genomic medicine and recent molecular evolution arising from population/environmental factors unique in time and geography and which have implications for the safe and efficacious use of drugs in different populations.
The higher relative weight of medication harms and benefits in this study confirms the importance of this information upon medication-taking decisions [ 36, 41] and suggests a need to reflect these preferences in future policies aimed at improving the safe and efficacious use of prescribed medications within the community.
Clinical pharmacology and therapeutics (CPT), the speciality responsible for training doctors in the safe, rational and efficacious use of drugs, has been progressively integrated into the undergraduate curriculum in the USA [ 6], United Kingdom [ 7], Netherlands [ 8], India [ 9] and Nepal [ 10] as a way of improving the prescribing knowledge and skills of junior doctors.
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Healthcare authorities, institutions, and orthopedic units in Finland are obliged to provide the National Agency for Medicines with information that is essential for monitoring past and current trends for the efficacious use of materials, approaches, and designs used in orthopedics.
Healthcare authorities, institutions, and orthopedic units in Finland are obliged to provide the National Agency for Medicines with information that is essential for monitoring past and current trends for the efficacious use of materials, approaches, and designs used in orthopedic medicine.
Re-framing future interventions and policies to support rational and informed individual patient choices, is the way forward to realising the full potential health and economic benefits from the efficacious use of medications.
Rapid response at the onset of the pandemic could ensure efficacious use of hospital beds and resources, e.g., cancel elective procedures and early discharge to community care.
The presence of inhibitors generally precludes the efficacious use of FVIII and FIX replacement therapy, especially in patients with high-responding and high-titre inhibitors, due to an anamnestic response.
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