The phrase "and efficacious in a" is correct and usable in written English.
It can be used when discussing the effectiveness or efficiency of something in a specific context or application.
Example: "The new treatment has been shown to be safe and efficacious in a clinical setting."
Alternatives: "and effective in a" or "and successful in a".
Comer and colleagues demonstrated that administration of 200 μg of intravitreal daptomycin was safe and efficacious in a rabbit model of bacterial endophthalmitis [13].
DNA vaccines offer several advantages, including the ability to express diverse antigens, tolerability in various hosts, ease of delivery, and stability for storage and distribution without the necessity of maintaining a cold chain; they have been shown to be safe and efficacious in a variety of animal models [2], [4], [12], [22], [48].
However a new oral formulation was recently presented [ 30, 31] which has been proven safe and efficacious in a 3-month phase II study including postmenopausal women [ 30, 31, 42- 45], and a dose of 0.8 mg taken bid is currently being assessed in phase III trials in OA.
For this prospective observational study, we hypothesized that CVVH with citrate as anticoagulant and buffer in replacement solution is safe and efficacious in patients with a bleeding tendency, without excluding those with liver disease.
In conclusion, our results suggest that CVVH with citrate-containing replacement solution is safe and efficacious in patients with a bleeding tendency, even in the presence of moderately severe liver disease, provided that safety monitoring is strictly applied.
One genetically and phenotypically stable vaccine candidate, rCR84G/F170SLY942A/L992C, was attenuated and efficacious in AGMs and is a promising live attenuated intranasal HPIV1 vaccine candidate suitable for clinical evaluation.
Everolimus 5 mg daily given orally and carboplatin AUC 4 administered intravenously every 3 weeks was both safe and efficacious in metastatic TNBC with a CBR of 36% and median PFS of 3 months.
We found the novel ROCK2-selective small molecule inhibitor KD025 dose-dependently safe and efficacious in both males and females, with a therapeutic window of at least 3 h.
These results show TNFR2 antibodies are potent and efficacious in vitro.
ONS is safe and efficacious in the treatment of medically intractable headaches conditions.
Laparoscopic cholecystectomy is safe and efficacious in children, and it compares favorably with traditional cholecystectomy in the pediatric age group.
