Main outcome measures were determined by severity and duration of response.
These generally focus on assessing the efficacy and duration of response to guide patient therapy.
The degree and duration of response to epidermal growth factor receptor (EGFR) inhibitors in EGFR mutated lung cancer are heterogeneous.
Secondary end-points included progression-free survival (PFS), overall response rate (ORR) and duration of response (DOR); safety end-points were also assessed.
Two large randomized studies that included patients with metastatic colorectal cancer have shown superior response rates for capecitabine compared with bolus regimens of 5-FU with equal times to progression, overall survival, and duration of response.
The criteria, timing and duration of response should be specified, and the potential effects of concomitant treatment and complications other than GVHD should be taken into account in assessing outcomes.
The objectives of the present analysis are to disect a class of turnover feedback models that have proven to be flexible from a mechanistic and empirical point of view, for the characterization of the onset, intensity and duration of response.
All variables were analysed for influence on the type and duration of response.
Secondary objectives included safety, progression-free survival (PFS), and duration of response (DR).
The primary objectives were to evaluate the response rate and duration of response.
Secondary endpoints include overall survival, time to progression, overall response rate, and duration of response.
