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Additionally, selection bias and dropout in the control group can be reduced.
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In addition, offering the intervention to all participants reduces the potential of dropout in the control group.
However, the dropout rate does not confirm this argument, as there were only 2 dropouts in the control group compared to 4 drop-outs in the treatment group.
There were 11 dropouts in yoga and 9 in the control group.
Compliance was high (only 1 dropout in the SK&P group, and 5 in the control group).
In summary, 123 patients completed the study with eight dropouts in the exercise group and six in the control group.
We created different types of missingness and different "directions" of dropout (patients in the treatment group dropped out when they had good outcomes, and patients in the control group dropped out when they had poor outcomes).
The dropout rate from the scheduled consultation reported by the GPs was 34%% in the intervention group and 44%% in the control group (p = 0.593).
There were more dropouts in the intervention group than in the control group, 10 in the intervention group and 4 in the control group.
Using mean (SD) effect sizes of 6.8 (8.8) in the intervention groups and 2.0 (7.2) in the control group, there was 90% power for the primary aim with 75 participants per arm and a dropout rate of up to 20%.
However, we expect a 50% dropout due to non-response and loss to follow-up, i.e. we will need 168 patients in total; 84 in the intervention- and 84 in the control group.
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