The phrase "and difficulty to detect" is not correct in standard written English.
It can be used when discussing something that is hard to identify or notice, but it needs to be rephrased for clarity.
Example: "The issue was subtle, with many underlying factors contributing to its complexity and difficulty to detect."
Alternatives: "and hard to identify" or "and challenging to notice."
Development of new drugs for Chagas disease is fraught with difficulty, not least because patients entering the indeterminate stage are asymptomatic and the difficulty to detect parasites then and in early chronic infections complicates any definitive assessment of cure.
Using such antibodies, we observed a strong decrease of fluorescence and the difficulty to detect biomarkers of mineralized cells (Fig. 4).
This may be due to the fact that these transcripts were cloned at lower frequency (only once) showing their lower abundance and subsequent difficulty to detect them [ 30].
Indeed, a reason invoked by plant molecular biologists to avoid experiments in natural environments despite the lab field gap is the perceived low reproducibility of results that would be generated under unpredictable fluctuating conditions (Izawa, 2015) and the difficulty to detect transcriptional signals of interest (Travers et al., 2007).
Even HRM is a promising method, it can be compromised by a low proportion of tumour cells in the analysed sample and by the difficulty to detect homozygous mutations, as the sensitivity of K-Ras mutations detection was only 5 10%.
The difficulty to detect and quantify contaminants of emerging concern in the environment stimulates the development of appropriate analytical methods.
Detectability: defines the difficulty to detect the attacks, ranging from easy (E) to difficult (D), and the deployed methods to detect the attacks.
This second problem was designed to increase the level of difficulty, to detect subtle differences in learning and memory.
The high concentrations of LTB4 detected in human saliva are in contrast to the difficulty to detect this lipoxygenase product in blood and urine samples.
