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The phrase "and difficulties of" is correct and usable in written English.
It can be used when discussing challenges or obstacles related to a particular subject or situation.
Example: "We need to address the challenges and difficulties of implementing this new policy."
Alternatives: "and challenges of" or "and obstacles to".
Exact(60)
They might be about the rewards and difficulties of living with difference.
This article describes both the comforts and difficulties of re-entry.
But they now say they have come to understand the many intricacies and difficulties of cancer research.
The Herd tackles forthrightly and with passion the discords and difficulties of a family with a severely disabled son.
Interviewed in their apartment before the wedding, Tom talked about the importance and difficulties of gay marriage.
He said the "dangers and difficulties" of crossing swollen streams and rivers had been explained to them.
"However, the complexities and difficulties of partnerships and collaborations provide a wider and more compelling field of analysis.
For much of his long working life, Degas was attracted to the pleasures and difficulties of the artist's materials.
"Into the Wild" is, on the contrary, alive to the mysteries and difficulties of experience in a way that very few recent American movies have been.
Few Palestinians can leave their homes to work, and the costs and difficulties of transporting goods have become prohibitive, aid workers say.
On the way they are beset by threats and difficulties of many kinds: harsh weather, local hostility, fear and discouragement, a murderous quarrel, a typhoid epidemic.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com