The phrase "and development of second" is not correct and lacks clarity in written English.
It seems to be an incomplete thought and would require additional context to be usable.
Example: "The project focuses on the research and development of second-generation technologies."
Alternatives: "and advancement of second" or "and progress of second".
Considerable progress has recently been made in understanding the structural biology of Abl and the molecular basis for resistance, facilitating the discovery and development of second generation drugs designed to combat mutant forms of Bcr-Abl.
However, β-carotene supplements which increase plasma β-carotene significantly, show no beneficial effects on mortality and development of second primary tumours in head and neck cancer patients [ 32, 33], and even increase the risk of developing lung cancer [ 10].
This was achieved by comparing the pregnancy outcomes, rates of disease relapse and development of second tumours to those of other women on our GTT database or in the general population.
The exploration and development of second-order nonlinear optical (NLO) materials in the middle- and far infrared (MFIR) region are important and high profile topics in the fields of NLO, solid-state chemistry and laser.
Loges, S., Schmidt, T. & Carmeliet, P. Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.
Design and development of first synthetic approach to the functionalized tetracyclic framework of structurally novel seco-tetracenomycin natural products saccharothrixones A C has been reported.
Our growing knowledge of transporter biology will greatly accelerate the discovery of novel drug targets and development of first-in-class therapies.
The initiation and development of first cracking at mid-point of the control slab and the slabs with fibers of 0.2 and 0.3% by volume (S2 and S3) took place at deflection Δ cr of 0.5 0.6 mm, respectively (Table 4).
61 X-ray crystallographic analysis of multiple mutant ABL alleles in imatinib-resistant patients was essential for the screening and development of second-generation TKIs.
Moreover, these shortcomings have restricted the application and development of second-generation sequencing technology to some extent and have necessitated the development of third-generation single-molecule sequencing technology [10 12].
In this review, current understanding of HIV-1 MIs is described and recent progress made toward elucidating the mechanism of action, target identification and development of second-generation MIs is reviewed.
