Sentence examples for and development of aggressive from inspiring English sources

This association between SYK deficiency and development of aggressive pro-B cell leukemia in infancy may be caused by a loss of SYK-induced phosphorylation of IK on activating serine residues S358 and S361 (Uckun et al., 2012).

There was a positive association between cigarette smoking and development of aggressive adenomas in the study population, especially a highly significant association between current smokers, both males (OR=2.50, 95% CI: 1.54 4.04) and females (OR=2.51, CI: 1.31 4.80), and risk of colorectal adenoma, when adjusted for age and NSAID use.

The disease severely impacts the patient's quality of life and can even cause early lethality in the most severe forms due to defects in skin barrier function leading to infections and development of aggressive skin squamous cell carcinoma (Carulli et al, 2013).

Amplification or overexpression of EGFR has been revealed to play a significant role in the progression and development of certain aggressive types of breast cancer [ 46].

According to epidemiological studies, low adiponectin levels are associated with elevated cancer risk and development of more aggressive neoplasms [ 4, 11, 48].

This approach demonstrates the fact that differential expression of particular miRNAs at germline level may dysregulate target hub genes in prostate cancer cells thereby leading to abnormal cell division and proliferation and the development of aggressive prostate cancer.

Peer rejection may be an important mediator in the link between difficulties in social understanding and the development of aggressive disruptive behavior [ 45], and may further interfere with the development of social understanding [ 31].

Among his innovations were the introduction of price tags and the development of aggressive advertising programs for his growing chain of stores.

An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients.

If the increased risk of prostate cancer and the development of aggressive tumours are confirmed in further studies of LS families, male gene carriers, especially of an MSH2 mutation might benefit from surveillance.

In fact, alterated expression and/or de-regulated function of Eph-ephrin system promotes tumorigenesis and development of a more aggressive and metastatic tumour phenotype.