Sentence examples for and destabilization of a from inspiring English sources

The exact molecular nature of this interaction is the subject of continuing studies, but it should lead us to a molecular understanding of how TTP promotes the deadenylation and destabilization of a specific set of target proteins.

This effect was later shown to be mediated through TRIM32 ubiquitination and destabilization of a pro-apoptotic SUMO-E3 ubiquitin ligase protein inhibitor of activated STAT Y (PIASy) which exhibited altered intracellular distribution in response to UVB/TNFα-treatment (29).

Collectively, our results demonstrate that inhibition of tumor-derived Hh signaling leads to inhibition of tumor angiogenesis and destabilization of vasculature with a concomitant decrease in recruitment of BMPCs into the tumor stroma.

MAP-microtubule binding is regulated through MAP phosphorylation, leading to the detachment of MAP from microtubules and destabilization of the microtubule as a consequence.

In contrast, agonist stimulation and destabilization of the actin cytoskeleton lead to an increased contribution from higher oligomers.

This effect being compounded on both chains causes a complete disruption of Zn2+ binding and destabilization of the dimer.

These morphological developments can result from abnormalities in chromatid packing and destabilization of the genetic material.

These data suggest that PC-PLC is involved in the progression and destabilization of established atheroma.

TIMP-2 may also inhibit the development and destabilization of the atherosclerotic plaques [ 15].

In the cytosol, CREBPP promotes polyubiquitination and destabilization of p53 [ 44].

The ANG cytoplasmic translocation enhances phosphorylation and destabilization of VE-cadherin and attenuates endothelial barrier function.