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Paired data were assessed using the Wilcoxon signed-rank test.
Nonparametric data were assessed using the Mann-Whitney test.
Continuous data were assessed using the Mann-Whitney U-test.
Normality of data was assessed using the Kolmogorov Smirnov tests.
Data was assessed using the Chi square test.
Data was assessed using the Analyst® QS software (PE Sciex Instruments, Toronto, Canada).
Normality of data was assessed using the Shapiro Wilk test.
Normality of data was assessed using the Kolmogorov Smirnov test.
The quantitative data was assessed using the median value.
Clinical and demographic data were assessed using a standardized protocol.
Safety and demographic data were assessed using summary statistics.
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