MUAC is better predictor of mortality, easier and less cumbersome to perform and therefore is recommended for use in community-based screening [ 22].
On the other hand, multiplex IHC assays are cumbersome to perform and the quantification of the signal is still not standardized across pathology laboratories.
However, until recently, the lack of 'adoption' of EEG-based electric source imaging in the clinical world has mainly been because the application of a high number of electrodes (i.e. between 100 and 200 or even more) was too cumbersome to perform routinely.
Traditionally, the diagnosis of CAN involves a number of tests, including the R-R response to deep breathing, postural changes and during Valsalva maneuver, or 24-h ECG recordings, which may be cumbersome to perform uniformly, especially in large multicenter trials such as ACCORD.
If repairs validated in the laboratory are too cumbersome to perform in vivo from a practical standpoint, technical ease should be a prerequisite measure, and the success of a repair technique should not necessarily be based on biomechanics alone.
Methods for determining equine SAA have been cumbersome to perform or require automated analysers.
Altogether, these issues make these studies extremely cumbersome to perform, especially when analyzing human samples.
The Rosendaal method [ 9], commonly used for Time in Therapeutic Range (TTR) calculations, is very cumbersome to perform in non-computerized settings.
MRI provides valuable diagnostic information, although it is cumbersome to perform in the acute phase in comatose patients who are undergoing mechanical ventilation.
Such tools are especially relevant for tasks that are cumbersome to perform manually, such as validating taxon names using a reference taxonomy, providing taxon sampling statistics, or pruning source trees so that they only contain taxa from a taxonomic group of interest.
