Sentence examples for and culminated in the identification of from inspiring English sources

Nevertheless, this empirical protocol generated the critical purified cells for a genome-wide panning for candidate genes encoding surface markers that were differentially expressed in RoSH-like cells versus ESCs, and culminated in the identification of CD9hi SSEA-1− cell population as RoSH-like cell population in differentiating EBs.

The search for the genetic defect itself pioneered many mapping and gene-finding technologies, and culminated in the identification of the HD gene, its mutation and its novel protein product in 1993.

When early members of this series were found to be potent time-dependent CYP3A4 inhibitors, two distinct strategies to address this liability were explored and this effort culminated in the identification of compound 31 as an optimized renin inhibitor.

This culminated in the identification of compound 31 as an optimized renin inhibitor.

This culminated in the identification of 36; a potent RET inhibitor with much improved selectivity against KDR.

This effort culminated in the identification of compound 18, an orally bioavailable, sub-nanomolar renin inhibitor even in the presence of human plasma.

This study culminated in the identification of compound 23 as a potent GR agonist with selectivity over the PR and MR nuclear hormone receptors.

This work culminated in the identification of the clinical candidate 15, which demonstrates preclinically the desired efficacy and safety profiles confirming its potential as an inhaled agent for the treatment of asthma.

Protein kinase resequencing at the Sanger Institute has culminated in the identification of 921 base substitution somatic mutations in 210 diverse human cancers types [12].

This procedure culminated in the identification of seven immunogenic peptides, three of these were derived from the 'human 1-8D gene from interferon inducible gene' (1-8D).

This comparison culminated in the identification of 114 pathways, 3 of which were significantly affected by higher gene expression variances in RA and 4 of which were significantly affected by higher gene expression variances in OA.