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This suggests a role for transformed embryonic kidney progenitor cells and CSC in the origin of these tumours (reviewed in Pode-Shakked & Dekel, 2011).
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This phenotypic co-association of CXCR6, a biomarker for asymmetric self-renewal in non-cancerous cells, with CSC activity in tumor-derived cells is evidence for a direct lineage relationship between TSSCs and CSCs in the case of melanocytic cells and melanoma, respectively.
In this study, we demonstrate evidence of a direct interaction between the EMT and CSCs in the highly metastatic AdCC subclone ACCS-M GFP.
BMI-1 is required for self-renewal of both NSCs and CSCs in the prostate (Lessard and Sauvageau 2003; Pardal et al. 2003).
Although sphere assays are being extensively used to evaluate stem cell activity in normal tissue and CSCs, in the majority of these cultures there is no definitive information as to which cells are being propagated.
Two companies, BT and CSC, are in the running for the work, which the unitary authority said would be part of a "new strategic partnership".
However, the notable advantages of nanomaterials, such as high drug load content, metabolism control, and controlled release, make nano-drug carriers great application prospect in cancer and CSC therapy in the future.
In this review, we discuss the current evidence surrounding the identification and microenvironmental control of stem cell populations in intestinal crypts and tumours as well as exploring the evidence supporting the existence of a quiescent stem and CSC population in the gut and other tissues.
holds, for all x, y in K. Propositions similar to above can be stated for the class of KSC and CSC mappings in the framework of CAT ( 0 ) spaces.
BT and CSC were in the running for contracts to run services including libraries, and benefit payments.
In addition, 12 patients with triple-negative breast cancer were recruited and ESA+CD44+CD24− lineage− CSC in the resected breast cancer tissues were isolated.
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