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Second, we selected our cases and controls based on more than one factor (i.e., the groups differed based on both CD8+ T cell activation and absolute CD4+ T cell counts).
The analyses presented here excluded about 10 to 15% of placebo group, and about 5% of active treatment group cases and controls based on an IQR outlier criterion as applied to the differences between baseline and one-year log-analyte concentrations.
A chi square test was performed to assess Hardy Weinberg equilibrium in the TN patients and controls based on allelic and genotypic frequencies.
One-way analysis of variance (ANOVA) Tukey's HSD was used to test whether each of residual mycotoxins in samples and controls based on TLC was significantly different (P < 0.05).
Fine matching of cases and controls based on genetic ancestry is an increasingly popular strategy to correct for such confounding, both in genome-wide association studies (GWASs) as well as studies that employ next-generation sequencing, where matching can be used when selecting a subset of participants from a GWAS for rare-variant analysis.
The genotype data would be re-analyzed after re-coding cases and controls based on each secondary trait.
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