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In these cases, the Aβ species produced may be secreted into the extracellular space, where their build-up can promote senile plaque formation, or they may remain within the cell, where their aggregation can trigger neurotoxic processes and contribute to the progression of AD [24].
This should create positive feedback loops which amplify the signal and contribute to the progression of meiotic maturation.
Both autoimmunity and vasculopathy appear to precede the onset of the disease, and contribute to the progression of fibrosis.
In sum, imbalanced levels of eicosanoids can induce modification of the microenvironment in the kidneys, eyes, nerves, and cardiovascular system and contribute to the progression of diabetes pathogenesis.
Perivascular adipose tissue can stimulate smooth muscle cell proliferation via release of hydrosoluble protein growth factor(s) and contribute to the progression of atherosclerosis (59).
Specifically, in human tumors, TAMs that have differentiated into the M2 phenotype act as "protumoral macrophages" and contribute to the progression of disease.
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Inflammation and oxidative stress contribute to the progression of diabetic cardiomyopathy (DCM).
Gender difference and nitric oxide deficiency contribute to the progression of many chronic kidney diseases.
Study finds a complex series of molecular, cellular, circuit and network-level changes contribute to the progression of Alzheimer's.
Additionally, implant design and trunnion geometries may contribute to the progression of component failure.
Macrophages are the principal cells involved in chronic inflammation and produce many effects that contribute to the progression of tissue damage and to consequent functional impairment.
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