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The polymorphism within cytokine genes might influence the susceptibility to, and contribute to the pathogenesis of the disease.
Bacterial biofilms are complex multicellular assemblies that exhibit resistance to antibiotics and contribute to the pathogenesis of serious and chronic infectious diseases.
Altered 1α,25(OH)2D3 level may play a role in the development of T2DM and contribute to the pathogenesis of liver diseases.
Although Aβ has multiple targets to exert its neurotoxicity, our findings suggested that GSK3β-induced mitochondrial fragmentation was, at least partially, mediated by Aβ toxicity and contribute to the pathogenesis of AD.
Mitochondrial protein acetylation increases in response to chronic ethanol ingestion in mice, and is thought to reduce mitochondrial function and contribute to the pathogenesis of alcoholic liver disease.
During inflammation and hypoxia, angiogenesis is induced to compensate for poor oxygenation; however, this may result in aberrant vasculature and contribute to the pathogenesis of chronic inflammation [7].
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Both genetic and environmental factors contribute to the pathogenesis of metabolic syndrome.
These findings provide new insights into pathways and therapeutic targets that contribute to the pathogenesis of AMKL.
Mechanistically, alterations in the structure and function of mitochondria contribute to the pathogenesis of NAFLD.
Excessive innate immune response could contribute to the pathogenesis of inflammatory and autoimmune diseases.
Microenvironmental conditions contribute to the pathogenesis of cancer and include altered cellular composition, extracellular matrix (ECM) deposition, and mechanical cues.
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