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In 1965, Clair Patterson published the first study to demonstrate that high levels of lead in the environment (water, air, soil) were man-made and constituted a potential health threat.
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These benefits were associated with reversal of potentially maladaptive mitochondrial metabolic alterations, and constitute a potential clinical therapeutic avenue for the dystrophic cardiomyopathy.
Strongyle parasites are ubiquitous in grazing horses and constitute a potential threat to equine health.
They may lead to effects seen in microelectronics or damage to solar cells and constitute a potential hazard for manned missions.
Periodontal diseases cause destruction of periodontium (tooth-supporting tissues such as gingiva and alveolar bone) and constitute a potential risk factor for certain systemic diseases (Agnello et al., 2017; Pihlstrom et al., 2005).
Another important cell type emerging in canalicular stage is the so-called lipofibroblast (LIF), which is involved in surfactant production through interaction with the AEC II and constitute a potential stem cell niche for AEC II stem cells.
Staff is generally an unstable variable, with wide variability in levels (staff skill mix) and ratios across settings and constitutes a potential source of efficiency differences.
One of the top most upregulated genes was the lipid metabolism gene PPARG that regulates adipocyte differentiation and constitutes a potential therapeutic target [ 38, 39].
Phospholipid biogenesis is crucial for the intracellular development of the parasite and constitutes a potential area for therapeutic intervention that has already been validated leading to a novel and promising pharmaceutical approach for the treatment of malaria [ 19, 20].
For example, Neurod2 is expressed within a wide temporal window (from embryonic day 10.5 throughout adulthood) outside of the proliferative zones and constitutes a potential regulator of critical aspects of differentiation and/or maintenance of different types of cortical excitatory neurons [ 8, 10].
Of the 69 alerts of this type, 41 alerts were true positive and 10 constituted a potential risk for the patient (that the physician had not recognized) but not a proven ADE.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com