The phrase "and constitute a large" is correct and usable in written English.
It can be used when describing a significant portion or amount of something in a formal or academic context.
Example: "The new policies and initiatives are designed to improve efficiency and constitute a large part of our overall strategy."
Alternatives: "and make up a significant" or "and represent a considerable".
Dutch road haulage companies are market leaders and constitute a large slice of such business in the EU.
Global NH3 emissions are projected to double by 2050 and constitute a large part of the Earth's reactive N pool4,5,6.
Many such Communist Party publications were introduced at the trial and constitute a large part of the evidence in this case.
Many early derashot from this era have been preserved in nonlegal sections of the Talmud and constitute a large portion of the Midrash (collected explanations of the underlying meaning of biblical texts).
Proofs of such statements are usually rather subtle and involved and constitute a large part of the subject of thermodynamics, but conclusions based on thermodynamic principles are among the most reliable results of science.
The report notes that young Europeans are the prime buyers of technologically-advanced mobile phones and constitute a large part of the potential consumers across Europe.
As particular stocks rise in price and constitute a larger portion of an index, there is another problem for investors who add to their fund holdings.
Public-sector workers are more likely to vote Labour, regardless of their social class, and constitute a larger proportion of the workforce in the north.When Labour increased public spending in the north it strengthened its position there.
The connate water accumulated in front of the injected water, and constituted a large fraction of the water that immiscibly displaced the oil from the core plug.
The discovery of bioactive compounds underpins many areas of basic biomedical research and constitutes a large part of medicinal chemistry and chemical biology.
POCD is likely to impair quality of life and constitutes a large burden on society when elderly patients prematurely lose their independence.
