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However in simulated intestinal fluid (SIF, pH 7.4) a slow and consistent release of the drug was obtained over period of 24 h.
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Further, the parameters for the consistent release of the cells from the biofilms were optimized; test showed that the number of cells released was uniform and reproducible.
The sporadic rise in human activities over the decades has led to the consistent release of various recalcitrant anthropogenic pollutants into water bodies, thereby causing a sharp drop in the quality of the ecosystem.
The PENTASA formulation also demonstrated consistent release of 5-ASA across individual tablets.
We did not brief some of the elected officials early enough to ensure consistent release of information to the public.
The very high contraceptive efficacy of implants comes from consistent release of low but highly effective levels of progestin in the blood.
The APRISO formulation demonstrated consistent release of 5-ASA across individual capsules at each pH (see Table 2 for SDs at pH 6.8).
Clinical PK analysis has shown a consistent release of hydromorphone over 24 hours, with steady-state plasma concentrations achieved by 48 hours (2 doses) and sustained throughout the 24-hour dosing interval [ 14, 15].
The consistent release of hydromorphone over 24 hours has been demonstrated in previous studies, in which steady-state plasma concentrations were achieved by 48 hours and sustained throughout the dosing interval [ 8, 28].
Preliminary studies aimed to select the optimal treatment for a consistent release of CSFs showed an increased GM-CSF secretion after a 24 h-incubation period with IL-1β (10 ng ml−1).
In preliminary studies, cells were stimulated with different combinations of cytokines (Table 1-wrap>) and interleukin-1ß (IL-1β, 10 ng ml−1, Roche) plus tumour necrosis factor α (TNF-α,10 ng ml−1, Roche) was selected as the optimal treatment for a consistent release of CSFs.
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