Sporadic reports throughout the latter half of the 20th century, however, have hinted at the presence of the parasite in these regions, the most convincing of which were the steady and consistent numbers of non-African travelers who returned to their countries of origin infected with malarial parasites that were subsequently identified as P. vivax (2 ).
However meningitis due to Cryptococcus neoformans accounted for significant and consistent numbers of cases, particularly in adults in 2000 2012, with the exception of the under-5 group, in whom cryptococcal meningitis was detected only from 2009 onward (Supplementary Figure 2).
A previous attack using the Pony botnet was described by the researchers as "hit-and-run operation," whilst this attack was carried out over a number of weeks with the hackers taking in a "fairly stable and consistent" number of passwords each day.
Finally, our adaptation of the mESC monolayer culture and differentiation method (Ying and Smith, 2003) showed that a relatively low and consistent number of TH+ neurons were detected in the culture system.
In addition, the effects of an additional round of amplification on gene expression profiles have been reported to be minor on the basis of high Pearson correlation coefficients of all genes (0.85 to 0.94) between one and two rounds of amplification [ 4, 10, 11] and of consistent numbers of differentially expressed genes detected between one and two rounds of amplification [ 12].
Fluorescence-activated cell sorter analysis of the spleen from 10- to 14-week-old Apoe−/− V H S107.1.42 +/+, Apoe−/− V H S107.1.42 +/ −, and Apoe−/− V H S107.1.42−/− mice demonstrated consistent numbers of B-1 and B-2 lymphocytes across all 3 genotypes, strongly arguing against a critical function of the V H S107.1.42 gene in the generation of the peripheral B-1 cell population.
Data extracted from the HCIS database during 2007 to 2009 indicated that there had been consistent numbers of pregnancy and delivery; 123 and 100 women attended ANC clinic during 2008 and 2009 while 57 attended in between the two years.
It is not surprising, then, that the largest and most consistent number of high-amplitude rhythmic transcripts were HIOMT and TrH, two genes involved in the melatonin biosynthesis pathway that are regulated by the circadian clock.
Rms deviations between all four Gal3C structures (Table S1) and the consistent numbering of water molecules in their active site areas (Table S2), electron density of the α and β anomers of lactose and hydrogen atoms, NMR spectra of histidine side chains, and ITC data, and NMR spectra of glycerol titrations.
All 7C8 residues were numbered according to the Chothia numbering scheme that compensates for length variability in the CDRs and generates a consistent numbering of the structurally conserved Fab framework region [35].
Although the semiparametric and two-step clustering approaches provided consistent number of groups and similar expected trajectories, consideration must be given to the fact that the identification of ten clusters was based on the number of groups suggested by the semiparametric approach because the clustering approach did not provide a single optimal number of clusters.
