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They can reveal aberrations not visible by other methods, and consequently facilitate the molecular identification of targeted genes.
The analysis of chromosomal alterations using these techniques could reveal new aberrations not visible by other methods, and consequently facilitate the molecular characterisation of target genes.
Met1166 is located in the interface between the αC-helix and the DFG-helix and mutations of this residue would probably destabilise the DFG-helix and consequently facilitate the shift of the αC-helix (Fig. 1B) (Bossi et al., 2010).
Concepts of epigenetic plasticity in cells, which upon niche disturbances stochastically select for epigenetic heterogeneity and consequently, facilitate the ability of cells to acquire abnormal characteristics, have been put forward (Ushijima and Asada, 2009; Feinberg and Irizarry, 2010).
The main steps for ethanol production from lignocellulosic biomass are pretreatment, hydrolysis, fermentation and distillation/purification. The pretreatment should enhance the fiber accessibility and consequently facilitate the subsequent steps of enzymatic hydrolysis and fermentation [ 7].
Methylation of CpG by Dnmt3a/3b in this promoter may induce the recruitment of ICBP90 (inverted CCAAT box binding protein of 90 kDa) and consequently facilitate the replacement of p300 by Dnmt1 in the repressor complex pRb2/E2F4/5/HDAC1/SUV39H1/Dnmt1 found in ERα- BC, MDA MB231 cells.
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The exact ability is especially important for users who utilize VR to do collaborative design, for it will greatly reduce the amount of on-line computations on operating substance-based interactions, and consequently facilitates the collaboration.
In tropical climate, (high temperature, high relative humidity and high annual rainfall) these organisms may secrete carbohydrates and growth factors which helps in the formation of biofilm (a three-dimensional structure regulating temperature and humidity) and consequently facilitates the growth of diverse microbial communities within it.
Unlike the −35 element which appears to be more heterogeneous in sequence, the −10 element plays an essential role in promoter binding by stabilizing the initial interactions between the RNAP holoenzyme and the DNA promoter sequence, and consequently facilitating the subsequent isomerization of the promoter to an open form, exposing the DNA template strand [38].
The DiaA tetramer stimulates multimerization of DnaA and consequently facilitates the melting of oriC DNA (Katayama et al. 2010).
The HMGA proteins induce these effects by directly binding to the DNA, modifying its conformation and, consequently, facilitating the binding of a group of transcriptional factors.
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