Sentence examples for and consequent inhibition of from inspiring English sources
mtCB1 receptors signal through intra-mitochondrial Gαi protein activation and consequent inhibition of soluble-adenylyl cyclase (sAC).
We tested some of the neuroprotective effects of sodium selenite in NPC cells by monitoring thioredoxin reductase (TR) expression, optimum H2O2 removal, and consequent inhibition of pro-apoptotic events including cytochrome c release and caspase 3 and 9 activation.
On the other hand, scar stimulation by pacing prevents correct impulse transmission, and consequent inhibition of myocardial contractility.
It combines dopaminergic effects, including selective and reversible MAO-B and dopamine reuptake inhibition, which are largely responsible for its effects on motor symptoms, along with non-dopaminergic properties, i.e. blockade of voltage-dependent Na+ and Ca2+ channels and consequent inhibition of glutamate release that is thought to confer neurorescue and neuroprotectant effects [20].
Inhibition of IκB-phosphorylation results in its accumulation and consequent inhibition of NF-κB transcriptional activity.
The discussion on TTR/A-Beta interaction and consequent inhibition of aggregation and toxicity reduction raised the hypothesis that mutations in the TTR gene or conformational changes in the protein induced by aging, could affect the sequestration properties.
In this study, we describe a novel antibody, 24F4A, which binds BDCA2 and leads to its internalization and the consequent inhibition of TLR9-induced IFN-I by pDCs both in vitro and in vivo.
In this study, we show that 24F4A, a humanized monoclonal antibody (mAb) against BDCA2, engages BDCA2 and leads to its internalization and the consequent inhibition of TLR-induced IFN-I by pDCs in vitro using blood from both healthy and SLE donors.
It has been suggested that HSP27 and HSP72 partecipate in oncogenesis since their overexpression and the consequent inhibition of apoptosis can increase the tumorigenic potential of cancer cells[ 6].
In contrast, MEK1 inactivation and the consequent inhibition of ERK1/2 pathway, caused only a slight and non significant decrease in the rate of cell proliferation induced by 10% FBS (Figure 2C).
Thus, we speculated that the activation of AMPK and the consequent inhibition of fatty acid synthesis could ultimately be a protective mechanism against the accumulation of SFA due to deficient SCD1 activity.
