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This type of research often involves retrospective recall of symptom onset by patients; such recall is subject to many types of error which may affect the accuracy, reliability and completeness of data collection.
Effective communication during consultations is the major determinant of the accuracy and completeness of data collection, influencing both the range and number of symptoms elicited, thus permitting a more precise assessment of the efficacy of treatment (Fallowfield and Jenkins, 1999).
Data on incident cases of cancer were obtained from the Babol Cancer Registry; issues related to methods, quality and completeness of data collection for this cancer registry are described elsewhere [ 9, 11].
This leads to variations in the care with which informed consent is obtained, diligence in application of inclusion and exclusion criteria, rigor of collecting information on concomitant medications and use of over-the-counter treatments, attention to timeframes of data collection, thoroughness of adverse event reporting, and completeness of data collection and recording [ 37].
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287 Trial investigators must often seek a balance between achieving a sufficiently long follow-up for clinically relevant outcome measurement, 122 288 and a sufficiently short follow-up to decrease attrition and maximise completeness of data collection.
Strengths of the present study include the large study size and the completeness of data collection.
Parameters measured within the feasibility trial will include recruitment and retention, practicality of collecting outcome measures, completeness of data collection, and data required for the assessment of cost-effectiveness.
Once again the requirement for computerisation to generate the FAM-splat in time for the meeting ensures that the ratings are entered into the database before each patient is discharged from the unit, and so supports the completeness of data collection.
Figure 1 shows the flowchart of ineligible/excluded men, completeness of data collection and attrition from the study between recruitment and 12 months post-treatment.
These have been further modified based on completeness of data collection and data quality evaluations from the pilot study.
Throughout the duration of the study, the completeness of data collection and compliance with patient enrolment will be quality assured.
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CEO of Professional Science Editing for Scientists @ prosciediting.com