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IL-1-/ mice showed the same influx of inflammatory cells and comparable degree of cartilage damage as control mice (Fig. 1), indicating that overexpression of IL-17 causes loss of IL-1 dependency in this model.
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Significant and comparable degrees of improvement were observed, regardless of baseline history of PsA.
In parallel experiments we performed direct cell counts to validate the alamarBlue® data, and observed a comparable degree of neurotoxicity in the presence of 40mM Cu II -Aβ1 40 (Figure S1).
It is worth mentioning that an increase in the dose of flagellin to 5 μg/mouse did not exert any further increase in the activation of MAPKs and NFκB, as shown by a comparable degree of ERK and IκBα phosphorylation in the different organs, suggesting that minute doses of flagellin are already sufficient to produce a maximal activation of these stress signaling cascades.
Fascinatingly, AM-MSCs and BM-MSCs exhibited comparable degree of immunosuppressive effect when they were co-cultured with activated T-cells.
Skin and mucosal wounds undergo a comparable degree of transcriptional changes except at 12 and 24 hours after injury.
TLR genes examined for polymorphism and divergence in Lissotriton newts exhibit a comparable degree of conservation and evolutionary constraint.
Lastly, as compared to controls obese patients experienced a comparable degree of dyspnoea and less leg fatigue on exertion.
Sites B2, B3, and B4 produce lower and fairly similar damage factors, indicating comparable degree of building damage.
In parallel, three age- and BMI-matched controls were studied before and after a diet and exercise intervention, which achieved a comparable degree of weight loss (14.8 ± 1.76 kg).
Fluorescence measurement of released RhB molecules revealed the acceleration of the molecular release upon 400-nm laser irradiation, whereas 800-nm laser irradiation did not induce a comparable degree of change compared with non-irradiated samples.
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