Here we successfully report the identification of significant and ontologically coherent changes in DNA methylation in a human genome-wide study of the effect of endurance exercise in muscle tissue, which was made possible by the combination of a well-controlled, prospective study design with a comprehensive, integrative bioinformatic analysis.
By combining these two time-domain experiments into a "coherent lock-in" measurement in the terahertz regime, where X-ray diffraction tracks coherent lattice motion and photoemission monitors the subsequent coherent changes in the electronic band structure, the deformation potential can be determined for this compound due to the single phonon mode.
Orbital forcing plays a pivotal role in driving coherent changes in Antarctic ice-volume and the carbon cycle, and thus global climate (Zachos et al., 2001a; De Boer et al., 2013).
Changing westerly winds in the Southern Hemisphere have caused coherent changes in the southern ocean ventilation.
We hypothesized that there would be coherent changes in the extent of phosphorylation of signaling molecules and of the expression and amounts of proteolytic enzymes that would match the changes in size and direction of measured aspects of muscle protein turnover.
Such processes are remarkably mirrored by the concomitant, coherent changes in several biochemical pathways, mechanistically linked to both proliferation and programmed cell death.
Frich, P. et al. Observed coherent changes in climatic extremes during the second half of the twentieth century.
"We are talking about dramatic, coherent changes in climate around the world, in the form of unprecedented rates of warming, increased continental drought, extreme flooding and wildfires.
Second, experimental modulation of voltage in vivo is a powerful method for making large-scale, coherent changes in anatomy.
To the extent that we understand the function of the behaviors, we can recognize these directions as coherent changes in many behaviors that together serve a common purpose.
