Sentence examples for and changes in modification from inspiring English sources

ChIP assays were done with antibodies to specific acetylated or methylated amino acid residues and changes in modification at NucB on the MMTV promoter were determined.

Increased expression and changes in modification(s) were observed for LRAG, a protein involved in granulocytic and neutrophil differentiation, and angiogenesis.

The same principle is true for histone-modifications that can be dynamically regulated in response to environmental stimuli, and changes in histone-modifications have been linked to the transmission of phenotypes across generations.

Variable-temperature experiments demonstrate both crystallization effects and changes in the modifications.

This leads to chromatin remodeling and changes in histone modifications to activate and repress target gene transcription [ 1– 3].

Genes that were correctly predicted as repression targets generally had the most differential features, including binding by Hairy and Gro, and changes in histone modifications.

These phenotypes included permanent growth arrest, elevated activity of senescence-associated β-galactosidase (SA-β-Gal), and changes in histone modifications [ 6].

However, inactivation of DNMT3a triggers other, apparently secondary, epigenetic changes, including DNMT3b-mediated hypermethylation and gene repression, and changes in histone modifications also linked to gene repression (Challen et al., 2012, 2014).

A mounting body of evidence suggests that epigenetic mechanisms may play a role in the carcinogenicity of arsenic, not only through aberrant DNA methylation but also through altered expression of microRNAs and changes in histone modifications (Ren et al. 2011).

In cancer, aberrant epigenetic silencing of tumour-suppressor genes is a common occurrence that is associated with abnormal DNA methylation patterns and changes in covalent histone modifications [ 1].

Changes in the actors and changes in their relationships reveal modifications in the coalitions that provide the network's structure.