Sentence examples for and causes the production of from inspiring English sources

Furthermore, we show that exposure of MoDCs to FMDV in vitro impairs MoDC function and causes the production of high amounts of IL-10, although no viral replication is required.

Avian infectious bronchitis virus (IBV), a gamma-coronavirus, infects the respiratory tract of chickens and causes the production of eggs with deformed and weakened shells [ 1, 2].

We investigated the Ca2+ response to ATP, which acts on Gq-coupled plasmamembrane receptors and causes the production of inositol 1,4,5 trisphosphate, thus releasing Ca2+ from the ER to mitochondria.

By cloning alternative CD46 partial alleles into a minigene expression system which was transfected and expressed in 293 T cells, we demonstrate that this mutation disrupts an ESE, and causes the production of an aberrant CD46-TV isoform.

In vitro cell line studies have shown that 25 μg/mL of 25-nm Ag-nps in murine neuroblastoma cells decreases mitochondrial function and causes the production of reactive oxygen species that could potentially contribute to neurodegenerative diseases (Schrand et al. 2008).

After stimulation with ATP (which functions on Gq-coupled plasma membrane receptors and causes the production of IP3, thus releasing Ca2+ from the ER through the IP3Rs), Akt-overexpressing cells display a very different behavior in the release phase, with an 86,7±1.9% decrease in the Vmax of released Ca2+ (Vmax: 14.32±2.11 μM/s control versus 1.9±0.27 μM/s m/p-Akt).

Fullerenes are found to travel to the brain, bind with lipids, and cause the production of oxidative stress compounds when fish are exposed to concentrations of only 1 ppm (Oberdorster 2004).

Therefore, free electrons are accumulated in the mitochondria, which react with oxygen and cause the production of superoxide.

The orthologue of Arl2 in T. brucei is required for cleavage furrow ingression during cytokinesis and knockdown causes the production of multinucleated cells [27].

Exposure to UV radiation, X-rays, environmental pollutants, toxic chemicals and excessive drug use causes the production of free radicals and reactive oxygen species that lead to oxidative damage in the kidney, liver and lungs [ 1].

It is known that LPS-stimulated TLR4 signalling leads to the activation of two major downstream signal transduction pathways: the MyD88/TIRAP pathway which results in the generation of various pro-inflammatory cytokines and chemokines and the TRAM/TRIF pathway which causes the production of Type I interferons important for adjuvanticity (Fig. 1).