The violent sexual assault, which is the scene that opens the film, sets the tone for a dark exploration in the ways in which exploitation and victimization can be internalized and later manifested in everyday life.
It is also recommended that the Programme take a more proactive and reflexive role, always within the framework of its agreements with Ecuador, and a sound communication strategy with local donors, through which concrete and immediate results will emerge so that the scope of this approach and the advantages of its results and outputs can be internalized.
Further, external stigma and discrimination can be internalized into an individual's self-concept, creating psychological distress and preventing PLHIV from accessing health care services and seeking social support [ 17].
Whereas small amphiphilic drugs can diffuse across the cell membrane, macromolecules like proteins, nucleic acids, as well as nano-and submicron-material can be internalized by cells only via the energy-dependent mechanism of endocytosis.
Immature DCs (iDCs) capture HIV-1 through CLRs [6] and captured virus can be internalized and rapidly transmitted to nearby CD4 T cells, in the form of an infectious synapse [7], [8].
Extracellular adenosine and 2′-deoxyadenosine can be internalized through ENT and deaminated to inosine and deoxyinosine by ADA.
Taken together, these results suggest that the externally administered Aβ42 becomes oxidized during incubation in the cellular environment and that dityrosine crosslinked oligomers (and possibly fibrils) can be internalized into lysosomes.
Furthermore, it has been demonstrated that tau aggregates can have a seeding effect whereby extracellular tau can be internalized and upon internalization, these seeds can induce the fibrillization of endogenous tau [ 36].
On the other hand, FACS and affinity-chromatography moieties can be internalized and thus do not perturb the viability and/or function of the cells.
