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This is accomplished both by allosterically activating the ER resident cholesterol esterification enzyme acylCoA cholesterol acyltransferase (ACAT) and by increasing the extent of transport of cholesterol to ACAT-accessible domains within ER membranes.
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These analyses suggest that HDACIs sensitise NB cells to TRAIL-induced apoptosis by increasing the extent of caspases activation and thereby enhancing the extent of the apoptotic process.
Dry matter intake was increased by increasing the extent of grain processing.
This effect promotes stray grain formation in the pool by increasing the extent of constitutional supercooling.
"The agreement will help to promote human rights in Bahrain by improving the quality of evidence which is used by the police and prosecutors, and by increasing the extent to which prosecutions and convictions are based on objective evidence".
Finally, increasing the degree of anonymity by re-running the experiment online increased the extent of norm transgressions slightly.
It was observed that the sulfation of Ti-SBA-15 increases the extent of transesterification by fourfold.
Thus, ADP increased the extent of activation by PII even when PII was present at a saturating concentration.
To increase the extent of the reservoir contacted by the injected gas, the gas is generally injected intermittently with water.
Conditioned medium from LNCaP pBabe vector control cells increased the extent of mineralisation, as shown by alizarin red S assay.
Myocardial reperfusion injury, as a separate event, can increase the extent of injury beyond that caused by ischemia alone.
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