Sentence examples for and burden in a from inspiring English sources

Indeed, chronic (∼30 weeks) topical application of small quantities (40 nmol per animal) of TBE-31 twice a week resulted in dramatically reduced tumor multiplicity and burden in a model of ultraviolet radiation-mediated skin carcinogenesis in SKH-1 hairless mice receiving azathioprine treatment [19].

A properly operating legislature apportions benefits and burdens in a way that balances competing interests.

This assessment provides a thorough estimation of their seriousness, preventability, and burden impact in a large population from a representative European region.

We showed recently that calcitriol augments adipocyte and muscle oxidative and inflammatory stress, whereas dietary calcium induced suppression of calcitriol decreases the oxidative and inflammatory burden in a mouse model of obesity (7, 16).

Three month oral administration of CDDO reduced plaque and microglial burden in a mutant APP transgenic mouse model of AD, with concomitant improvement in spatial memory by Morris water maze [ 117].

An additional barrier that may be intrinsic to healthcare is the deeply personal nature of the way that any disease produces illness and illness burden in a particular individual.

*Due to small number of participants in some groups Fisher's exact test was used The results of this study show a general pattern of diminishing quality of life with the increasing psychical and physical burden in an individual.

"But the criticism of Merkel is also on the rise — she should have reacted earlier, with more zest, and shoulder the burden in a more decisive way".

Systemic inhibition of HIF-1α by 2ME2 significantly decreased osteolytic lesion area and reduced tumor burden in a prevention model of MDA-MB-231 breast cancer bone metastasis, consistent with the previous studies using 4T1 cells [42].

In this study we examined the association between pulmonary function and cadmium body burden in a subcohort of the Normative Aging Study, a community-based study of aging.

Importantly, neutralizing monoclonal antibodies raised against the mouse α4 integrin subunit also decreased osteolysis and overall tumor burden in a mouse model of myeloma bone disease [ 19].