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Parada and colleagues provided evidence that cancer stem cells may be responsible for GBM recurrence by using a nestin-ΔTK-IRES-GFP mouse model that labels quiescent subventricular adult neural stem cells, and breeding this transgenic mouse to a well-established mouse model of gliomagenesis (hGFAP-Cre; Nfl fl/+; p53 fl/fl; Pten fl/+) (ref. 7; Fig. 1).
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We would like to thank Rowan Tweedale and Peter Cook for editorial assistance and The University of Queensland School of Biomedical Sciences Animal Facility for maintaining and breeding the animals used in this study.
Whole genome sequence and expressed sequence tags (ESTs) of the eucalypts paved way for introduction of molecular genetics and breeding in this genus.
The nine newly developed polymorphic markers recognise a sufficient number of varying loci to perform further studies on the conservation and breeding of this medicinal cultivar.
Understanding genetic diversity and population structure of wild S. japonica populations will aid in the management, conservation and breeding of this marine macroalga.
Moreover, it seems unlikely that conventional selection and breeding within this tetraploid germplasm will lead to the development of varieties that are safe to individuals with CD.
Although genetic gain has been made through conventional selection and breeding efforts, this could be substantially improved through the application of molecular methods.
With an objective to enhance utilization of the identified SNPs/InDels for chickpea genetics and breeding applications, this study reports a database containing large-scale variants along with characterization in the genome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com