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These findings permit further investigations to both better characterize this association in larger cohorts and begin to elucidate the underlying mechanism(s) of this phenomenon.
Using the microfluidic chamber, we can unambiguously determine the nature of progeny virions targeted to axons and begin to elucidate the effectors of viral transport.
Our view is that such systematic experiments will help clarify the way in which both length and sequence contribute to the probability of DNA looping, and begin to elucidate the mechanisms whereby transcription factors act over long genomic distances.
This provides an opportunity to generate evidence about the range and nature of positive and negative impacts on health and the social determinants of health and begin to elucidate their causal pathways and the specific components of regeneration which influence health.
Given the high specificity of H. volcanii to caspase catalytic activity our findings strongly suggest that recently developed in situ inhibitor trapping techniques (Tu et al., 2006; Mohr and Zwacka, 2007) are a promising avenue to identify these enigmatic proteins and begin to elucidate their physiological roles and molecular evolution.
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In summary, these data highlight the complex genetic architecture underlying common traits even within a single gene, and specifically, begin to elucidate how NOS1AP genetic variants modulate QT interval.
Therefore, the present study was initially undertaken to test the assumption that PP1γ2 plays a singular, but as yet unknown role among PP1 isoforms in the development of mammalian male germ cells (particularly spermatids), and to begin to elucidate the biochemical basis of its uniqueness.
Santoro and Dulac begin to elucidate the signalling pathway that connects neuronal activity to H2be expression, which may well reveal the identity of other activity-sensitive pathways as well.
The aims of this study were to use comparative genomics to identify the genetic diversity between multiple prevalent phage types and try to begin to elucidate the genetic basis for the predominance of certain phage types and host adaptation.
In a second paper, Smits and colleagues [ 5] begin to elucidate the molecular mechanisms of the genetic variants.
To begin to elucidate cellular signaling pathways that mediate these anti-proliferative and pro-apoptotic effects we examined expression levels of several proto-oncogenes and tumor suppressors.
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