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They often have under insulated tanks and are not optimised as integrated systems.
J-values were extracted directly from the splittings in the spectrum, and are not optimised.
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This reaction was found to be robust and scalable, and was not optimised to improve the yield of the product 66.
However, CSCG does not necessarily converge on a global minimum, and is not optimised for efficiency, which are two areas for possible improvement.
Those methods were different from the ones evaluated in this report, and were not optimised for picogram amounts of input RNA.
Although these technologies offer great promise for patient with cardiac failure, in-vitro differentiation protocols are not optimised and currently produce cell populations with high phenotypic heterogeneity.
Recent developments in portable analytical instrumentation have made this more accessible to heritage institutions, but many commercial systems are not optimised for the specific requirements of manuscripts and works on paper.
This also leads to an immediately testable prediction from our model: Wild-type cells are not optimised for yield, but for growth rate and it is possible to obtain cells with increased cell yield from artificial evolution experiments designed to avoid (or minimise) cell-cell competition.
The difficulties associated with introducing ART are well known: there is no eradication of the virus, therefore treatment is lifelong; adherence lapses occur; drug formulations are not optimised; drug toxicities are frequent; drug-drug interactions complicate management and drug resistance requires special attention.
These platforms are not optimised for the mobile generation or for immediacy.
As with Sigfox's network, the idea here is that normal cellular networks today are not optimised for IoT deployments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com