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The following quality items were used to assess the methodological quality and risk of bias in the studies [[30],[31]]: eligibility criteria, adequacy of sample size, reporting of randomization, reporting of blinding, avoiding selective reporting, description of intervention details, description of outcome measures, description of adverse effects, and adequacy of data analysis.
The DSMB is responsible for monitoring the project, subject safety and adequacy of data quality.
The Registration, Evaluation, Authorisation and Restriction of Chemical substances (REACH) process in the EU also has guidance addressing relevance, reliability, and adequacy of data (ECHA 2008).
All focus group participants were asked to offer their feedback and reflections regarding the accuracy and adequacy of data coding and of the key themes that were identified by the project team.
However, the definitions of some of these (e.g. flexibility and acceptability) would need further refinement, and a number of these characteristics were rated as low in importance and had little consistency between raters (e.g. legislative requirement for data collection, and adequacy of data for injury surveillance).
To ascertain the internal and external validity of the eligible RCTs, two pairs of reviewers (BM, WH; and MSc, Mst) working independently and with adequate reliability determined the adequacy of randomisation, concealment of allocation, blinding of outcome assessors and adequacy of data analysis (was intention-to-treat-analysis performed?) (internal validity).
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The task force is also meant to assess the "availability and adequacy" of crime data, and troubleshoot ways to improve data gathering "in a manner that will aid in the understanding of crime trends".
The NPSC did not judge the scientific merit of the conclusions reached by the sponsor of each mock submission but rather considered the experimental design, organization of data, and adequacy of the information available to support the hypothesis, including the relationship of the genomics data to the general toxicology data.
Electronic data validation systems will ensure that data sets conform to the agreed data models and the quality and adequacy of the submitted data will be regularly reviewed from a clinical perspective.
This pilot will be used to identify problems with the research design/processes; refine data collection and analysis; assess adequacy of data sources; examine selection and enrolment processes; and assess the participants' perspective on participating.
Knowing uncertainties and their kind, sources, and consequences would help in assessing the reliability, relevance, and adequacy of the available data and enable better acting under uncertainty, e.g., for political or scientific decisions concerning prioritizing research or regulation.
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