Sentence examples for and activated upon from inspiring English sources

p53 is usually phosphorylated and activated upon oncogene activation and DNA damage resulting in growth arrest and DNA repair or cell death induction, depending on the extent of the damage (Vousden & Lane, 2007).

This involves fielding cars with modified versions of Bosch's previous radar sensors, since those were designed to work with today's advanced driver assistance feature, and activated upon detecting motion.

Also, estimation of the internalized fraction can be of significant importance to the prediction of efficacy of a particular antibody-drug conjugate dose, as the antibody-drug conjugate is frequently administered in a pro-drug form and activated upon internalization.

The protein tyrosine kinase ZAP-70 is recruited to the phosphorylated ITAMs and activated upon phosphorylation of tyrosine 319 [1].

Both SHP-1 and PTP-1B, which are important regulators of inflammation [25], [26], are rapidly cleaved and activated upon infection or contact with the exoproteome.

Since MST2 is cleaved and activated upon apoptotic stimuli and is required for DNA damage-induced apoptosis in different types of cells, we initially examined if extracellular cell survival signal regulates MST2 cleavage and activation.

T cells are easy to collect and are fully equipped to proliferate and activate upon antigen recognition.

In contrast to bacterial and plant PLDs, mammalian PLD is latent in its basal activity and is activated upon stimulation of cells by a wide variety of agonists including growth factors and cytokines (Billah and Anthes, 1990).

DNA-PK is part of the phosphoinositide 3-kinase related kinase family with ATM and ATR and is activated upon association with DNA [ 19].

Many Ral-GEFs, such as RalGDS, Rlf/Rgl2, Rgl, RPM and Rgr, contain a Ras-binding domain and become activated upon interaction with the GTP-bound form of Ras [5], [6].

This promoter is active in HeLa as well A549 cells and is activated upon treatment of cells by TNFα.