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HSL variants in which Ser552 and/or Ser554 were mutated to Ala or Glu retained both lipolytic and non-lipolytic activity and were phosphorylated by PKA and activated to a similar extent as the wild type enzyme.
Two examples are Mmp7 and Mmp9, both of which were expressed and activated to a greater degree in the mammary glands of BN rats, relative to ACI rats.
We found that both kinases are recruited and activated to a similar extent at all investigated DSBs, in a manner that appears to be independent of the pathway used for subsequent repair.
Similar(57)
Rac and Cdc42 exert their functions by binding and activating to a large collection of their effector molecules.
Ceramic foam substrates of various porosities were coated with novolak resin, which was then subsequently carbonised and activated to develop a pore structure.
What scares me the most is that so many of the people that are on the sidelines, that would have to be activated -- motivated and activated to make a movement, are taking it for granted.
The SIS was then placed bilaterally and activated to produce an initial intrusive force of approximately 500 g (Figure 3a,b).
MMP-12 is expressed as a 54-kDa inactive proenzyme and is activated to a 45-kDa active enzyme by removal of the propeptide sequence.
MMP-10 is secreted as a 53-kDa proenzyme and is activated to a 47-kDa mature protease.
Renal function was preserved to a higher degree, and cell survival and antioxidant systems were activated to a greater extent.
The contralateral motor and sensory cortices are also activated to a greater extent during 40 and/or 100 Hz stimulation.
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