DAG and PA are two interconvertible lipids that influence membrane architecture and that act as essential signaling molecules that activate various downstream effectors, including master regulators of local protein synthesis and actin polymerization.
Based on our findings with FGF-7, we speculate that heparin may disrupt the interaction of heparin-binding growth factors such as FGF-7 with heparan sulfate proteoglycans that are produced by fibroblasts and that act as essential co-factors for the growth factors.
Caspase-3 was a member of the cysteine-aspartic acid protease family and acted as an essential executive enzyme in the apoptosis signal pathway.
In addition, experimental evidence indicates that reactive astrocytes play important roles in regulating CNS inflammation, and that astrocyte scars act as essential functional barriers that restrict the migration of inflammatory cells and infectious agents and limit spread into adjacent healthy tissue (Sofroniew, 2005; Sofroniew, 2009; Sofroniew and Vinters, 2010).
Thus, the let-7 miRNAs of C. elegans and D. melanogaster both act as essential regulators for proper development at the larva-to-adult transition.
Although the two dimensions of work-family balance practices are different in their content, formats and effects, they ultimately act as essential resources provided by organizations.
This idea questions the FRTA and rather suggests that ROS act as essential signaling molecules to promote metabolic health and longevity [ 97].
"Urban street trees provide a canopy, root structure and setting for important insect and bacterial life below the surface; at grade for pets and romantic people to pause for what pets and romantic people pause for; they act as essential lofty environments for song birds, seeds, nuts, squirrels and other urban life.
BRs act as essential regulators of cell elongation, cell division and differentiation and participate in many aspects of development (Clouse, 2001; Bishop and Koncz, 2002; Haubrick and Assmann, 2006).
