This governance response must be able to govern established or potential users, be flexible and adaptive in response to unexpected and unpredictable dynamics and be able to transform in the face of unpredictable future uses of this vast area.
We chose leukemic cells expressing MLL-ENL for several reasons: first, MLL-ENL is a potent oncogene and is able to transform and immortalize progenitor cells at various levels of myeloid differentiation, although high-doses of growth factors are still needed for in vitro culture, most likely to substitute for a lacking class I mutation in these cells [27], [51].
But it is her voice, rich and thrillingly able to transform accent and register, which marks her out as the real thing.
However, despite lack of ligand-binding EGFRvIII has a constitutively active receptor tyrosine kinase and is able to transform fibroblasts and to confer enhanced tumorigenicity to cancer cells both in vitro and in vivo (Huang et al, 1997; Damstrup et al, 2002; Pedersen et al, 2004).
Interestingly, JEG-3 cultures release human chorionic gonadotrophin, human placental lactogen, progesterone, and are able to transform steroid precursors into estrone and estradiol.
Such efficacy requires risk reduction and self-regulation skills, but possessing the skills and being able to transform them into action under difficult circumstances are two different matters (10).
But from then on, he tried to listen and was able to transform into someone who has been in front of the lens all his life.
The next DNC chair should also know a thing or two about fundraising and be able to transform the party into the receptacle for all the grassroots energy and passion that poured into the Obama campaign.
The A. tumefaciens virulence system has evolved to respond to phenolic wound hormones such as acetosyringone, and is able to transform a range of fungal species if acetosyringone is provided in vitro.
Analyses of these genetically engineered mice demonstrate that Δ16HER2 constitutively homodimerizes on the tumor cell plasma membrane and is able to transform mammary epithelium in vivo through the oncogenic properties mediated by the downstream Src kinase signaling circuitry, making this splice variant a likely candidate for the transforming form of the HER2 oncoprotein.
