The phrase "and a significant block" is correct and usable in written English.
It can be used when referring to a substantial portion or group of something, often in contexts like demographics, resources, or support.
Example: "The proposal received backing from various stakeholders, including a significant block of local businesses."
Alternatives: "and a considerable segment" or "and a major portion".
Most ruthenium atoms were retained in the nuclear compartment, particularly in HCC1937 cells, after 24 h of incubation, and produced a significant block at the G2/M phase.
The government has done precious little to pursue tax avoidance domestically and has been a significant block to international tax reform at the OECD and EU.
Excusing himself while he placed a lunch order, Mr. Anderson returned to say that he was not surprised to hear from Pardus, either, because he knew that hedge funds and other shorter-term investors held a significant block of Delta's shares.
However, BCL11B- ΔC-2 and wild-type BCL11B overexpression caused a significant block of cell cycle at G0/G1 which correlated well with the DNA-damage resistance.
Ancestor replicates were also scored in each block, and in no case was there a significant block effect for ancestors: Kruskal-Wallis χ = 3.44 (df = 2), 2.26 (df = 1), and 3.64 (df = 1), P = 0.18, 0.13, and 0.41, respectively, for plate growth, liquid growth, and slug distance.
But in a crowded field, his opponents have struggled to win a significant block of voters, and many lack steady financing.
A significant block effect was detected and a QTL mapping analysis was performed using data from each block separately, as well as using a lsmeans model, accounting for the effect of each block.
Only the combination of AEE788 with dovitinib caused a significant block in the PI3K/Akt/mTOR pathway and resulted in strong anti-tumor activity.
But Doug Muzzio, a professor of public affairs at Baruch College, said that the poll also revealed that a significant block of people do not like the mayor and consistently oppose him.
On further scrutiny of the sporadic cases, it was noted that three individuals also had a significant block of homozygosity overlapping this interval (DCR106, DCR311 and DCR324).
