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Tsang, Zhu, and Oudenaarden [31] outlined two types of miRNA circuits, as shown in Figure 7. Type I circuits: miRNAs and their corresponding targets are regulated together, implying short-term modulation of protein translation and a regulation of homeostasis of gene function.
Such increase is specific, since it does not affect FXN-1 or FXN-2); therefore, the underlying mechanism(s) should include both an enhancement of gene transcription and/or of mRNA half-life and a regulation of differential splicing.
The cell being a highly compartmentalized and dynamic entity requires for its survival the precise transport of certain molecules from one compartment to another and a regulation of this transport depending on its current physiological state.
This effect of ANP has been attributed to an antagonism of catecholamine-mediated renal vasoconstriction [ 52], a cGMP-mediated direct cytoprotective action on hepatocytes [ 54] and a regulation of Kupffer cell function [ 55], respectively.
In this study, we validate that Psn overexpression in wing imaginal discs induces an ER stress and we show that this ER stress triggers both cell death and a regulation of tissue homeostasis.
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Therefore, this study illustrates these environmental concerns and provides a strategy for a regulation of short-chain PFASs within REACH.
The results provide immunophenotypic evidence for a regulation of RAMP1 and sGC at the level of the trigeminal ganglion.
The adjustment of RR therefore leads to a regulation of etCO2 and PaCO2[ 34].
We illustrate this methodology for the following applications: a two zones temperature regulation and a frequency regulation of a 3-bus system.
The proper timely and spatial activation of these pathways requires fine tuning and a tight regulation of the proteins involved.
We also found a significant up-regulation of focal adhesion, apoptosis, the p53 signalling pathway, and an increased regulation of the actin cytoskeleton (Fig. 2).
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