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There was no increase, but rather a decrease at 24 h of ribose-5 phosphate and a prominent decrease in NADP+ at both 16 and 24 h (data not shown and Figure 1).
A significant increase of DIABLO was detected in the mitochondria-free cytosolic fraction, and a prominent decrease of DIABLO was detected in the mitochondrial fraction of DMD iPSC-CMs when compared with control iPSC-CMs, indicating the cytosolic release of DAIBLO from the damaged mitochondria in DMD iPSC-CMs.
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Both NUP98-HOXA9 aNUP98-HOXA9/N51S51S caused a prominent decrease in the expression of CD11b, consistent with a block in myeloid differentiation.
A closer look at the lattice parameters a, b, c, and β reveals a prominent decrease of the lattice parameter b (–2.6 %) in contrast to the lattice parameters a (+0.9 %) and c (–0.8 %).
Under the A1B and B1 scenarios, REMO projects a prominent decrease in rainfall in most parts of West and Central Africa and a positive rainfall trend on the windward side of the Guinean Mountains (~ 8°N, 12°W) and over the Horn of Africa [see Supplemental Material, Figure 2 (http://dx.doi.org/10.1289/ehp.1103681)].
Several studies have reported that a chronic shift of myocardial substrate preference in the diabetic heart resulted in a prominent decrease in glucose and lactic acid oxidation, and an increase in fatty acid oxidation [ 4, 5].
Transcript knock-down by stable Snail shRNA significantly blocked GD-induced necrosis in MDA-MB-231, HepG2, and A549 cells, as revealed by a prominent decrease in the population of cells that had intact pink nuclei in HO/PI staining (Figure 4C and S3).
For the reference CLSI method, a visual reading was made after 24 hours of incubation, and the lowest concentration that produced a prominent decrease in turbidity (≥ 50%) relative to that of the drug-free control well was recorded as MIC.
Histological and physiological analyses of BAT showed in adult wild-type mice, a marked suppression of BAT growth concurrent with a prominent decrease in lipolytic and thermogenesis activities.
Treatment with ATO caused a prominent decrease of GSH and T-AOC level compared with control group (P < 0.01).
Age- and drug-induced malfunction of thyroid gland resulted in a prominent decrease of glycerolipid synthesis which may promote DAG accumulation in liver.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com