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Recent mass ultrasound screenings in Tibetan pastoral communities of Sichuan Province, People's Republic of China, documented an average AE prevalence of 2%5(5 ) and a maximum prevalence of 14.3% (6 ) in humans.
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Use of hormonal (non-contraceptive) agents exceeds use of contraceptive agents by age 45 49, and increases to a maximum prevalence in the age group 50 54.
To detect the most prevalent chronic disease diagnosis, hypertension, at a maximum prevalence rate of 22% +/- 2.5% in each of the 4 age groups, 10,740 respondents (3,580 per site) were needed.
Adding the healthy carriage hypothesis to H0 implies higher prevalence rates for both sexes with a maximum prevalence equal to 41.9% for female and 33.8% for male (Table 3).
Pregnancy hypertension was uncommon, with a maximum prevalence of 8.71percentt if conflicting reports were accepted.
However, there were geographical variations (Table 1) with a maximum prevalence in Lemmu Bilbilo Woreda (3%).
Chronic hypertension was rare, with a maximum prevalence estimate of only 1.05percentt even if discrepant reports were accepted.
Larger numbers of BSE-negative animals would be required to achieve these levels of confidence for a maximum prevalence <1 per 10 million cattle (Table 1, Figure 2).
Assuming a maximum prevalence of 50% (worst case scenario) at pre-intervention for all domains, it was calculated that using a 5% significance level and having a minimum of 407 patients would give the study 80% power to detect a reduction in prevalence of 10% in each of the five SCNS-SF34 domains and one NA-ACP domain post-intervention.
Min. and Max.: minimum and maximum prevalence rates.
Table 1 presents the mean rates and 95% confidence intervals for each one of the types of prevalence, as well as the minimum and maximum prevalence rates, and the heterogeneity statistics (Q and I).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com