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The phrase "and a large majority" is correct and usable in written English.
It can be used when discussing a significant portion of a group or population in a context where you are presenting data or opinions.
Example: "The survey results indicated that a large majority of participants favored the new policy changes."
Alternatives: "and a significant majority" or "and a vast majority".
Exact(60)
And a large majority of rank-and-file Republicans as well as Democrats favor popular election.
Prominent party leaders -- and a large majority of those in Congress -- distance themselves from the effort.
After all, over 80% of American voters, and a large majority of Republicans still haven't heard of him.
More than 10,000 hedge funds are registered worldwide, and a large majority are small and anonymous.
Unlike European countries and a large majority of OECD countries, the US has abandoned policies that require the sharing of infrastructure with competing broadband providers.
And a large majority recommends that we continue this, even though it's extra work for them they got to do it every Sunday night.
Most Americans don't want to hear any more about the topic, and a large majority would like Ken Starr, the independent counsel, to end his investigation.
They are commonplace events, and a large majority of galaxies show signs of interactions, including tidal tails or other morphological distortions.
"In Rwanda, the conflict was between a small minority and a large majority," he said, referring to the history of Tutsis dominating the Hutu majority.
Lib Dem and Green party supporters are most likely to consider it good (85% each) and a large majority (70%) of Labour supporters concur.
Nearly half of those surveyed said they watch what they eat and a large majority said they limit their alchohol consumption.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com