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In protoplasts, we identified 14 genes that had several isoforms with dIF >20 and a considerably increased expression (Supplementary Table S2).
When we determined the joint effect of the risk alleles of STAT4 and two recently identified independent risk alleles in IRF5, we observed a multiplicative increase in OR by a factor of 1.82 for each additional risk allele and a considerably increased risk of SLE (OR = 5.83) for those 18% of the SLE patients who carried four or more risk alleles.
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4. Given that in high-risk samples children of parents with BPD, ASPD, and NPD show a considerably increased risk of mental health problems, we hypothesized that a milder, yet significant, increased risk would be seen in families from a community sample.
Our study may be of particular interest because its findings confirm the effectiveness of preventive home visits in a sample of community-dwelling people who were quite elderly (aged 80 years or older, mean age 85.1 years), and so had a considerably increased risk of falling as well as institutionalization.
Although few in number, women with negative HPV test and positive cytology had a considerably increased risk of CIN2+ (Fig. 3).
When we determined the joint effect of the risk alleles of IL18 and TLR4, we observed a considerably increased risk of GCA ORR, 3.7) for those 25% GCA patients who carried three or more risk alleles compared with those who carried none.
Integrated systems of passive and active pedestrian countermeasures offer a considerably increased potential for head injury reduction compared to either of the two systems alone.
Obesity is not only associated with physical incapacity and psychological distress but also with a considerably increased risk of type 2 diabetes, cardiovascular disease, respiratory difficulties, certain cancers and premature mortality.
Severe burnout is associated with a considerably increased risk for all-cause sickness absence [ 5].
This advances optical micromanipulation to a considerably increased range of particle sizes.
For the hydrogen and oxygen evolution reactions, pc behaved as a depolarizer and considerably increased the coulombic efficiencies of both reactions.
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