Sentence examples for ancient sequence from inspiring English sources

Although our approach of using an extant Y. pestis reference template for bait design precluded our ability to identify genomic regions that may have been present in the ancient organism and were subsequently lost in CO92, genomic comparisons of our ancient sequence against its closest outgroups may yield valuable insights into Y. pestis evolution.

A secure date for the East Smithfield site of 1348 1350 allowed us to assign a tip calibration to the ancient sequence and thus date the divergence time of the modern genomes and the East Smithfield genome using a Bayesian approach.

Scattered substitutions, which usually accumulate in aDNA as a result of post-mortem spontaneous damage reactions were observed [36] [41], while consistent substitutions shared by all clones for a given segment were believed to represent the authentic ancient sequence.

On figure 3 (t1 = 0.1), the Fst increases regularly as a function of the proportion of ancient sequence in the second subset (0.001 for n1/nB = 0.1 and 0.085 for n1/nB = 1) with dramatically increasing power (5 % and 72).

The vertebrate tetraspanin family has many features which make it suitable for preserving the imprint of ancient sequence evolution and amenable for phylogenomic analysis.

The vertebrate tetraspanin superfamily has several advantages which make it suitable for preserving the imprint of ancient sequence evolution and amenable for phylogenomic analysis.

The distribution of intron phase itself showed no direct relation to the ancientness of the sequence since the subset of introns that are located in ancient sequences has a similar phase distribution as introns in the general population (Fig. 7B).

To further elucidate the relationship between our Yakutian sequence and contemporary and extirpated brown bear populations, we included an analysis of the mtDNA CR, which included a larger temporal range of modern and ancient sequences.

The 12 ancient sequences were from different time points as it has been shown that even a small sample of aDNA sequences with widely distributed and accurate ages are sufficiently powerful to produce precise estimates for mutation rate and timescales39.

Despite the short read length of our ancient sequences and the highly repetitive nature of the Y. pestis genome, 2,221 contigs matching CO92 were extracted, comprising a total of 4,367,867 bp.

But the Australian study "suggests that if we saw more ancient sequences we might get a very different picture than we get from looking only at the DNA of living populations".