The phrase "ancient operational" is not a standard expression in written English and may cause confusion.
It could be used in contexts discussing historical methods or systems of operation, but clarity is essential.
Example: "The ancient operational techniques used by early civilizations reveal much about their ingenuity and resourcefulness."
Alternatives: "historical operational" or "primitive operational".
A more comprehensive study will be needed to evaluate the extent of HGT in whole sets of ancient operational and informational genes.
This means that the two concepts - the pre-translational code and the more ancient operational code of tRNA aminoacylation preceding the classic code for reading mRNAs - may tell actually one and the same story, rather than two different ones.
Furthermore, the pre-translational stereo-chemical hypothesis for the code origin [ 12, 16] and the hypothesis of the ancient operational code preceding the canonical one [ 26] do not contradict but might, in fact, strengthen each other if the acceptor arm is older than the anticodon arm, but both have a common ancestor.
This sub-code implies primacy of anticodons in the genetic code origin, but for simplest ("primordial"?) amino acids such as Ala and Gly, recognition of their proto-tRNAs by putative r-aaRSs might have been more acceptor- than anticodon-targeted, i.e. associated with the ancient operational code rather than the classic one (see [ 20] for details of this seeming "paradox").
The robustness of informational genes against transfer was previously contrasted with the rampant transfer among lineages of ancient metabolic (operational) genes [ 6, 8].
That is partly because they cling stubbornly to ancient traditions of operational independence.
The eastern route, which runs alongside the ancient Grand Canal, is expected to be operational by 2013.
This description gets us closer to making the case for what might be better described as operational wisdom (similar to what the ancient Greeks referred to as phronesis, usually translated as "practical wisdom").
For example, the operational definition of segmental duplications excludes ancient duplications that were formed by the same mechanisms long ago but that have since degraded below 90% sequence identity [39].
Seated in his spacious office in the embassy's B Section annex, which had been built in the thirties with a nod to ancient Athens, he generated both an intel report and an operational proposal for his branch chief.
The operational code embodied in the acceptor stem is very ancient, and the second base pair was originally the only (and therefore the most important) base pair in coding.
