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Throwing off the covers On the rise The noose tightens ReprintsThe IS's advance is particularly grim for the Yazidis, a religious minority for whom Sinjar is an ancient hub.
Ahmed Wali was suspected of being a drug kingpin and accused of being a CIA proxy, but his killing has unsettled this ancient hub of southern Afghanistan, and deepened the sense of uncertainty.
Alternatively, the ancient hub of the network may accumulate compensatory mutations that allow it to interact better with modern nodes.
Predictably, modifying an essential component of a protein network, such as its hub, with an ancient construct is most likely to cause the modern organism to be maladapted when the ancient hub is not functionally equivalent to the modern hub.
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The siege of Palmyra, an ancient Silk Road hub with magnificent ruins and an ancient temple as well as a storied mythology, has drawn concerns that Isis may raze the ruins like they did at several historic sites in Iraq's Nineveh, where the terror group holds sway.
Nevertheless, a trip to Cairo would be incomplete if you did not see the Egyptian Antiquities Museum, the Coptic Museum, the Muhammed Ali Mosque (one of the largest in the world and a rich example of the city's long occupation by the Ottomans), the charming Gayer-Anderson Museum and the Khan Al-Khalili bazaar, the city's ancient commercial hub.
(Aleppo, Syria's second-largest city, is an ancient trade-route hub not far from the Turkish border).
There were fears for the magnificent ruins of the city, an ancient silk-road hub and one of the best-preserved sites from antiquity, after Isis routed the regime garrison last week following a seven-day siege.
The image of the militants stalking the ruins of the ancient oasis, a hub of the Silk Road, has been a propaganda coup highlighting the impotence of the international community.
By plane, car and rail he has journeyed to Kashgar, an ancient Silk Road trading hub in China's far west, Mohe, at the country's northernmost tip, and to the balmy island of Hainan, which recently opened the world's only high-speed rail "loop line".
The most recent town abandoned by the Malian Army and taken by the rebels was the ancient city and tourist hub of Timbuktu.
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