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mtDNA haplogroups, as a product of ancient adaptation to environment, were formed during the evolution and migration of modern human and presented continental specific distributions (Wallace, 2005).
In this framework, ancestral alleles reflect ancient adaptation.
The pattern of spending most of their life outdoors is thought to result from an ancient adaptation to surviving on wild plants that produce suitable seeds [32].
This set of data might reflect an ancient adaptation between codon usage and tRNA positions of an original vertebrate mt-genome.
An evolutionary conserved and ancient adaptation pathway is the heat-shock response which, interestingly, activates molecular chaperones not only in response to heat-induced protein unfolding but also to unfolding caused by heavy metal ions, ethanol, or other toxins [ 3].
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Work within the Functional Synthesis has determined the phenotypes of ancient proteins, the functional consequences of ancient amino acid replacements, the selective causes of ancient adaptations, the origins and consequences of molecular epistasis, the origins of novel phenotypes, and the mechanisms underlying gene duplication and functional divergence.
The associated evolution of on-plant (serotiny) and soil seed storage, and later ant dispersal, affirms them as ancient adaptations to fire among flowering plants.
Regions that differ in copy number between subspecies can be informative about ancient adaptations that may have led to species-specific phenotypes [ 38].
Coop et al. [ 27] found most evidence for selection between continental groups suggesting that these are ancient adaptations that potentially occurred during the colonisation of continents.
Remarkably, some features thought to be the result of adaptation of C. glabrata to a pathogenic lifestyle, are present throughout the Nakaseomyces, indicating these are rather ancient adaptations to other environments.
Fireproneness among Gondwanan floras can now be traced back to the fiery Cretaceous and trait assignment affirms serotiny and soil seed storage, and later ant dispersal, as ancient adaptations to fire among flowering plants.
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