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Because most of the Y chromosome remains unchanged from father to son, the proportions of Sephardic and Moorish ancestry detected in the present population are probably the same as those just after the 1492 expulsions.
Because most of the Y chromosome remains unchanged from father to son, the proportions of Sephardic and Moorish ancestry detected in the present population are probably the same as those just after the 1492 expulsions, assuming no further emigrations since then.
The high degree of mixed ancestry detected was not surprising, as 36 individuals from the Santa Cruz breeding facility were sampled from a known "progeny" pen [4].
This highlights a widely recognized characteristic of self-declared ancestry: that it is not always an adequate indication of the genetic ancestry detected by a set of markers and their subsequent analysis [33].
Additionally, a GWAS for insulin resistance and related phenotypes in 2,684 Indian Asians (including subsequent analyses in 11,955 individuals of Indian Asian or European ancestry) detected an association of rs12970134 located 154 kb downstream of MC4R with waist circumference (p = 1.7×10−9).
Low pairwise Fst values between Tunisian populations, shared ancestry detected between them in unsupervised hierarchical clustering when setting k to 37, and reticulations observed between Tunisian populations on the phylogenetic tree (Fig. 4), all suggest high levels of gene flow between the three populations.
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Within these catchments, even higher levels of native ancestry were detected: all large alpine lakes (belonging to the Danube catchment) were dominated by genes of Danube ancestry, with levels of >90% in Ammersee and Starnberger See (1.2) and >80% in Chiemsee and Waginger See (1.1).
Thus, a sex-biased ancestry is detected in the Noir Marron gene pool.
With 85%, the highest proportion of Elbe ancestry was detected in the Nord-Ostsee-Kanal (2.1), a brackish environment connecting the North Sea with the Baltic Sea.
The lack of association between local genetic ancestry at SCN10A and QRS duration may be due to the fact that this locus is not responsible for the global ancestry signal detected here.
Indeed, other ancestries are detected in uniparental systems, in a sex-biased manner, contradictory to the Gold Coast and the Bight of Benin origin.
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Justyna Jupowicz-Kozak
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